Scholarly article titled “Per- and polyfluoroalkyl substances (PFAS) exposure in biota and remediation strategies: Toxicological and biochemical perspectives” by Hossain et al., (2025) published in the Journal of Hazardous Materials Advances. The article discusses PFAS exposure, its toxicological impacts, and remediation strategies, with a focus on biochemical perspectives.
This comprehensive review by Hossain et al. (2025) examines the pervasive presence of per- and polyfluoroalkyl substances (PFAS) in environmental biota and assesses their toxicological and biochemical impacts. The authors highlight the persistence, bioaccumulation, and widespread distribution of PFAS compounds, emphasizing their potential health risks to wildlife and human populations.
Key Points:
Environmental Distribution and Bioaccumulation: PFAS are detected in various ecosystems, accumulating in aquatic and terrestrial organisms, leading to biomagnification through food chains.
Toxicological Impacts: The review details adverse health effects, including endocrine disruption, immunotoxicity, and carcinogenic potential, linked to PFAS exposure.
Biochemical Mechanisms: The authors explore biochemical pathways affected by PFAS, such as interference with lipid metabolism, oxidative stress induction, and disruption of cellular signaling.
Remediation Strategies: The article evaluates current and emerging remediation techniques, including advanced oxidation processes, activated carbon adsorption, bioremediation, and nanotechnology-based methods, emphasizing the importance of sustainable and effective solutions.
Future Perspectives: Emphasizing the need for stricter regulations and innovative remediation technologies, the authors advocate for further research into biochemical pathways to develop targeted detoxification approaches.
Citation :
Hossain M.M., Nawaz, MZ., Dar, MA., et al. (2025) Per- and polyfluoroalkyl substances (PFAS) exposure in biota and remediation strategies: Toxicological and biochemical perspectives. Journal of Hazardous Materials Advances 17, 100579. https://doi.org/10.1016/j.hazadv.2024.100579.
Reported :
Hossain LAB, Center For Biology, Ecology and Environmental Science.